欢迎广州大学生命科学学院!

关跃峰

2024年04月01日 

 

1.基本情况:

关跃峰,男,博士,教授,博士生导师,闽江学者特聘教授。1999-2003复旦大学,学士学位。2003-2008中国科学院上海植生所,博士学位。2008-2010,美国加州大学伯克利分校,博士后。2010-2012,美国密苏里大学哥伦比亚分校,博士后。2012-2014,中国科学院,上海逆境植物生物学研究中心,副研究员。2014-2022,福建农林大学,海峡联合研究院,教授。2022至今 广州大学,生命科学学院,教授。

 

2.科研:

课题组隶属遗传学方向,研究方向是大豆重要性状调控机制解析与精准育种。实验室面向我国大豆种业振兴战略需求,基于大豆高效基因编辑技术,聚焦研究根瘤固氮和种子品质重要性状形成的分子基础,并解析这两大性状的协同调控关系。结合以上创新技术和理论依据,开展“高产优质、高附加值、环境友好”性状的大豆精准育种。以通讯或共同通讯作者在Nature PlantsMolecular PlantNature CommunicationsPlant Biotechnology Journal等期刊发表论文20余篇,论文总引用2000余次。任Frontiers in Pant ScienceNew Crops、生物技术通报等杂志编委。

 

3.教学:

主讲本科课程《生物育种与技术》,博士生《基因编辑技术》。

 

4.重要科研项目清单:

1、国家自然科学基金面上项目,糖酵解途径中磷酸甘油酸激酶参与花粉管极性调控的研究,63万,2016.01-2019.12    主持人 

2、国家自然科学基金面上项目,大豆海藻糖酶GmTRE参与磷调控结瘤固氮的分子机制,60万,2018.01-2021.12     主持人 

3、国家自然科学基金面上项目,大豆碳代谢介导氮阻遏固氮活性的分子机制,58 2021.01-2024.12 主持人

4、国家十三五重点研发计划专项作物器官发育与养分高效利用的互作机制(子课题),100万,2016.07-2020.12     研究骨干

5、福建省科技重大专项,福建重要经济作物的基因改良,100   2016.05-2019.04子课题负责人  

6、广州市校联合项目,大豆根瘤响应氮素转录调控网络研究,100万,2024- 2025-

7、农业部科技创新重大项目,耐盐碱、耐瘠薄基因编辑新技术, 75万元,2023-092025-12

 

5.近期发表代表性论文(截止至202310月)

1.        Zhong, X., Wang, J., Shi, X., Bai, M., Yuan, C., Cai, C., Wang, N., Zhu, X., Kuang, H., Wang, X., Su, J ., He, X., Liu, X., Yang W., Yang, C., Kong, F.*, Wang, E.*,Guan, Y.*(2024) Genetically optimising soybean nodulation improves yield andprotein content. Nature Plants in press

2.        Bai, M., Lin, W., Peng, C., Song, P., Kuang, H., Lin, J., Zhang, J., Wang, J., Chen, B., Li, H., Kong, F., Jia, G.,* and Guan, Y.* (2024).Expressing a human RNA demethylase as an assister improves gene-editing efficiency in plants. Molecular Plant. 17(3):363-366.

3.        Wang, X., Qiu, Z., Zhu, W., Wang, N., Bai, M., Kuang, H., Cai, C., Zhong, X., Kong, F., Lü, P.*, and Guan, Y.*(2023). The NAC transcription factors SNAP1/2/3/4 are central regulators mediating high nitrogen responses in mature nodules of soybean. Nature Communications 14, 4711.

4.        Lin, W., Kuang, H., Bai, M., Jiang, X., Zhou, P., Li, Y., Chen, B., Li, H., and Guan, Y.*(2023). Multiplex genome editing targeting soybean with ultra-low anti-nutritive oligosaccharides. The Crop Journal 11, 825-831.

5.        Bai, M., Hu, X., Lin, W., Peng, C., Kuang, H., Zhong, X., Li, Y., Chen, B., Wang, J., Li, H., Kong, F.*, and Guan, Y.*(2024). Development of PmCDA1-based high-efficiency cytidine base editors (ChyCBEs) incorporating a GmRad51 DNA-binding domain in soybean. New Crops.1,10001

6.        Bai, M., Yuan, C., Kuang, H., Sun, Q., Hu, X., Cui, L., Lin, W., Peng, C., Yue, P., Song, S., and Guan, Y.*(2022). Combination of two multiplex genome-edited soybean varieties enables customization of protein functional properties. Molecular Plant 15, 1081-1083.

7.        Fu, M., Sun, J., Li, X., Guan, Y.*, and Xie, F.* (2022). Asymmetric redundancy of soybean Nodule Inception (NIN) genes in root nodule symbiosis. Plant Physiology 188, 477-489.

8.        Zhang, Z., Wang, J., Kuang, H., Hou, Z., Gong, P., Bai, M., Zhou, S., Yao, X., Song, S., Yan, L., and Guan, Y.*(2022). Elimination of an unfavorable allele conferring pod shattering in an elite soybean cultivar by CRISPR/Cas9. aBIOTECH 3, 110-114.

9.        Bai, M., Yuan, J., Kuang, H., Gong, P., Li, S., Zhang, Z., Liu, B., Sun, J., Yang, M., Yang, L., Wang, D., Song, S., and Guan, Y.* (2020 ). Generation of a multiplex mutagenesis population via pooled CRISPR-Cas9 in soya bean. Plant Biotechnology Journal 18, 721-731.

10.    Wang, S., Liu, S., Wang, J., Yokosho, K., Zhou, B., Yu, Y.-C., Liu, Z., Frommer, W.B., Ma, J.F., Chen, L.-Q.*, Guan, Y.*, Shou, H.*, and Tian, Z.* (2020b). Simultaneous changes in seed size, oil content and protein content driven by selection of SWEET homologues during soybean domestication. National Science Review 7, 1776-1786.

11.    Wang, J., Kuang, H., Zhang, Z., Yang, Y., Yan, L., Zhang, M., Song, S., and Guan, Y.*(2020). Generation of seed lipoxygenase-free soybean using CRISPR-Cas9. The Crop Journal 8, 432-439.

12.    Li, R., Qiu, Z., Wang, X., Gong, P., Xu, Q., Yu, Q.-b., and Guan, Y.*(2019). Pooled CRISPR/Cas9 reveals redundant roles of plastidial phosphoglycerate kinases in carbon fixation and metabolism. The Plant Journal 98, 1078-1089.

13.    Wang, J., Zhou, P., Shi, X., Yang, N., Yan, L., Zhao, Q., Yang, C., and Guan, Y.*(2019). Primary metabolite contents are correlated with seed protein and oil traits in near-isogenic lines of soybean. The Crop Journal 7, 651-659.

14.    Chen, W., Gong, P., Guo, J., Li, H., Li, R., Xing, W., Yang, Z., and Guan, Y.* (2018). Glycolysis regulates pollen tube polarity via Rho GTPase signaling. PLoS genetics 14, e1007373.

15.    Yang, N., Jiang, J., Xie, H., Bai, M., Xu, Q., Wang, X., Yu, X., Chen, Z., and Guan, Y.*(2017). Metabolomics reveals distinct carbon and nitrogen metabolic responses to magnesium deficiency in leaves and roots of soybean [Glycine max (Linn.) Merr.]. Frontiers in Plant Science 8, 2091.

 

 

6.联系方式:

工作邮箱:guan@gzhu.edu.cn 

谷歌学术:Guan Yuefeng