欢迎广州大学生命科学学院!

董利东

2024年12月11日 

 

1. 基本情况:

基本情况:董利东,男,中共党员,博士,教授,博士生导师,国家自然科学基金优秀青年科学基金项目获得者2024)和广东省自然科学基金杰出青年科学基金项目获得者2023),广州学者青年拔尖人才(202420116月毕业于东北农业大学农学院,获得农学学士学位;20146月毕业于东北农业大学农学院,获得农学硕士学位;20176月毕业于东北农业大学农学院,获得农学博士学位;20185月起任广州大学生命科学学院生物科学系教师。

 

2. 科研:

科研:团队隶属于学院十四五规化的遗传学和植物学方向。主要从事控制大豆产量相关性状基因的发掘与调控网络解析及分子设计育种研究。克隆了多个大豆生态适应性关键基因;揭示了野生大豆适应高纬度长日照地区的遗传基础;阐明了栽培大豆在适应低纬度短日照地区和高纬度长日照地区的进化轨迹和遗传基础;进一步完善了大豆生态适应性分子调控网络。提出了大豆在不同种植区域的最优基因组合,对培育高产稳产大豆品种具有重要的指导意义。从20185月起先后主持国家自然科学基金优秀青年科学基金项目、青年科学基金项目、重大科学基金项目子课题、广东省自然科学基金杰出青年科学基金项目、广州市校(院)联合资助科学基金项目。截止至202410月发表论文50多篇,其中以第一作者(含共同第一)或通讯作者(含共同通讯)身份,在Nat. Genet.Nat. Comm. Mol. Plant PNAS Curr Biol. 等国际著名期刊发表SCI论文20篇;并参与发表20SCI论文。

 

 

3. 教学

教学:主讲本科课程《找基因与转基因》、《生物多样性保护与利用》、《上帝的手术刀之基因编辑》、《生命科学与人类生活》

 

4. 重要科研项目清单(截止至202410月)

1. 国家自然科学基金委员会, 优秀青年科学基金项目, 32422066,大豆分子遗传学与分子育种2025-01-01 2027-12-31200万元,主持, 在研 。

2. 国家自然科学基金委员会, 重大项目子课题, 32090065,大豆高产稳产品种的分子设计,2021-01-01 2025-12-31200万元,主持, 在研 。

3. 国家自然科学基金委员会, 青年科学基金项目, 32001508,大豆E1及其靶标基因遗传互作调控光周期开花的分子通路研究,2021-01-01 2023-12-3124万元, 已结题 主持。

4. 广东省基础与应用基础研究基金委员会, 广东省自然科学基金-杰出青年项目, 2023B1515020063, 大豆节间距关键基因AIL1的克隆和功能研究,2023-01-01 2026-12-31100万元,在研, 主持。

5. 广州市科学技术局, 市校(院)联合资助项目,202102010389,大豆生育期基因E1调控开花性状分子机制的研究,2021-04 2023-0320万元,已结题, 主持。

 

5.  近期重要科研项目清单(截止至202410月)

1. Gao CS, Yuan JZ, Lu JW, Ye W, Zhi JY, Li YL, Li WW, Sun MM, Kong FJ, Liu BH*, Cheng Q*, Dong LD*. (2024) COL3a simultaneously regulates flowering and branching to improve grain yield in soybean. Plant Biotechnol J, doi: 10.1111/pbi.14489.

2. Fang C, Sun ZH, Li SC, Su T, Wang LS, Dong LD, Li HY, Li LX, Kong LP, Yang ZQ, Lin XY, Zatybekov A, Liu BH*, Kong FJ*, Lu SJ*. (2024) Subfunctionalisation and self-repression of duplicated E1 homologues finetunes soybean flowering and adaptation. Nat Commun, 15: 6184.

3. Dong LD, Li SC, Wang LS, Su T, Zhang CB, Bi YD, Lai YC, Kong LP, Wang F, Pei XX, Li HY, Hou ZH, Du HP, Du H, Li T, Cheng Q*, Fang C*, Kong FJ*, Liu BH*. (2023) The genetic basis of high-latitude adaptation in wild soybean. Curr Biol, 33:1-11.

4. Dong LD, Hou ZH, Li HY, Li ZB, Fang C, Kong LP, Li YL, Du H, Li T, Wang LS, He ML, Zhao XH*, Cheng Q*, Kong FJ*, Liu BH*. (2022) Agronomical selection on loss-of-function of GIGANTEA simultaneously facilitates soybean salt tolerance and early maturity. J Inter Plant Biol, 64: 1866–1882.

5. Lin XY†*, Dong LD, Tang Y, Li HY, Cheng Q, Li H, Zhang T, Ma LX, Xiang HL, Chen LN, Nan HY, Fang C, Lu SJ, Li JG, Liu BH*, Kong FJ*. (2022) Novel and multifaceted regulations of photoperiodic flowering by phytochrome A in soybean. Proc Natl Acad Sci USA, 119: e2208708119.

6. Dong LD†*, Cheng Q, Fang C, Kong LP, Yang H, Hou ZH, Li YL, Nan HY, Zhang YH, Chen QS, Zhang CB, Kou K, Su T, Wang LS, Li SC, Li HY, Lin XY, Tang Y, Zhao XH, Lu SJ*, Liu BH*, Kong FJ*. (2022) Parallel selection of distinct Tof5 alleles drove the adaptation of cultivated and wild soybean to high latitudes. Mol Plant, 15:308-321.

7. Dong LD, Fang C, Cheng Q, Su T, Kou K, Kong LP, Zhang CB, Li HY, Hou ZH, Zhang YH, Chen LY, Yue L, Wang LS, Wang K, Li YL, Gan ZR, Yuan XH, Weller JL*, Lu SJ*, Kong FJ*, Liu BH*. (2021) Genetic basis and adaptation trajectory of soybean from its temperate origin to tropics. Nat Commun, 12: 5445.

8. Li ZB, Cheng Q, Gan ZR, Hou ZH, Zhang YH, Li YL, Li HY, Nan HY, Yang Cn, Chen LN, Lu SJ, Shi WQ, Chen LY, Wang YP, Fang Co, Kong LP, Su T, Li SC, Kou K, Wang LS, Kong FJ*, Liu BH*, Dong LD*. (2021) Multiplex CRISPR/Cas9-mediated knockout of soybean LNK2 advances flowering time. Crop J, 9(4): 767-776.

9. Chen LY, Nan HY, Kong LP, Yue L, Yang H, Zhao QS, Fang C, Li HY, Cheng Q, Lu SJ, Kong FJ*, Liu BH*, Dong LD*. (2020) Soybean AP1 homologs control flowering time and plant height. J Inter Plant Biol, 62 (12): 1868-1879.

10.  Bu TT, Lu SJ, Wang K, Dong LD, Li SL, Xie QG, Xu XD, Cheng Q, Chen LY, Fang C, Li HY, Liu BH, Weller JL., Kong FJ*. (2021) A critical role of the soybean evening complex in the control of photoperiod sensitivity and adaptation, Proc Natl Acad Sci USA, 118(8): e2010241118.

11.  Wang YH, Xu ChJ, Sun JF, Dong LD, Li MM, Liu Y, Wang JH, Zhang XM, Li DM, Sun JZ, Zhang YT, Shan JM, Li WB, Zhao L*. (2021) GmRAV confers ecological adaptation through photoperiod control of flowering time and maturity in soybean. Plant Physiol, 187(1): 361-377.

12.  Li YL, Hou ZH, Li WW, Li HY, Lu SJ, Gan ZR, Du H, Li T, Zhang YH, Kong FJ, Cheng YH, He ML, Ma LX, Liao CM, Li YR, Dong LD*, Liu BH*, Cheng Q*. (2021) The legume-specific transcription factor E1 controls leaf morphology in soybean. BMC Plant Biology, 21: 531.

13.  Lu SJ, Dong LD, Fang C, Liu SL, Kong LP, Cheng Q, Chen LY, Su T, Nan HY, Zhang D, Zhang L, Wang ZJ, Yang YY, Yu DY, Liu XL, Yang QY, Lin XY, Tang Y, Zhao XH, Yang XQ, Tian CN, Xie QG, Li X, Yuan XH*, Tian ZX*, Liu BH*, Weller JL*, Kong FJ*. (2020) Stepwise selection on homeologous PRR genes controlling flowering and maturity during soybean domestication. Nat Genet, 52: 428–436.

14.  Cheng Q, Gan ZR, Wang YP, Lu SJ, Hou ZH, Li HY, Xiang HT, Liu BH*, Kong FJ*, Dong LD*. (2020) The soybean gene J contributes to salt stress tolerance by up-regulating salt-responsive genes. Fron Plant Sci, 11: 272.

15.  Yu KY, Wang JS, Sun CY, Liu XQ, Xu HQ, Yang YM, Dong LD*, Zhang D*. (2020) High-density QTL mapping of leaf-related traits and chlorophyll content in three soybean RIL populations. BMC Plant Biol, 20(1): 470.

16.  Cheng Q, Dong LD, Su T, Li TY, Gan ZR, Nan HY, Lu SJ, Fang C, Kong LP, Li HY, Hou ZH, Kou K, Tang Y, Lin XY, Liu BH*, Kong FJ*. (2019) CRISPR/Cas9-mediated targeted mutagenesis of GmLHY genes alters plant height and internode length in soybean. BMC Plant Biol, 19: 562.

17.  Cheng Q, Dong LD, Gao TJ, Liu, TF, Li NH, Wang L, Chang X, Wu JJ, Xu PF* Zhang SZ*. (2018) The bHLH transcription factor GmPIB1 facilitates resistance to Phytophthora sojae in Glycine max. J Exp Bot, 69(10): 2527–2541.

18.  Fan SJ, Dong LD, Han D, Zhang F, Wu JJ, Jiang LY, Cheng Q, Li RP, Lu WC, Meng FS, Zhang SZ*, Xu PF*. (2017) GmWRKY31 and GmHDL56 enhances resistance to Phytophthora sojae by regulating defense-related gene expression in soybean. Fron Plant Sci, 8: 781.

19.  Dong LD, Cheng YX, Wu JJ, Cheng Q, Li WB, Fan SJ, Jiang LY, Xu ZL, Kong FJ, Zhang DY, Xu PF*, Zhang SZ*. (2015) Overexpression of GmERF5, a new member of the soybean EAR motif-containing ERF transcription factor, enhances resistance to Phytophthora sojae in soybean, J Exp Bot, 66(9): 2635-2647.

20.  Cheng Q, Li NH, Dong LD, Zhang DY, Fan SJ, Jiang LY, Wang X, Xu PF*, Zhang SZ*. (2015) Overexpression of soybean isoflavone reductase (GmIFR) enhances resistance to Phytophthora sojae in soybean, Fron Plant Sci, 6: 1024.

 

6. 联系方式

工作邮箱:dong_ld@gzhu.edu.cn